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Digestive Enzyme Complex - 60 capsules

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Original price €16,90
Original price €16,90 - Original price €16,90
Original price €16,90
Current price €15,04
€15,04 - €15,04
Current price €15,04
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At the Digestive Enzyme Complex from GN is a highly concentrated and comprehensive blend of digestive enzymes. These support the Digestion and can thus help ensure an optimal supply of important macro- and micronutrients to the body. Thus, all nutrients arrive where they are needed and digestion promotes an optimal Muscle buildinginstead of standing in its way. Digestive Enzyme Complex from GN Laboratories - because in the end only results count.

  • 1100 mg digestive enzymes per serving
  • Promotes the absorption of important amino acids
  • Supports digestion
  • Contains lactase
  • Patented, innovative digestive enzyme matrix DIGEZYME®.
  • Easy to dose capsule form
  • Highest quality - Made in Germany
Nutritional values and ingredients
CompositionPer capsule% of the reference amount (NRV*)
Betaine HCL200 mg**
Digezyme®150 mg**
Bromelain 1200gdu/g100 mg**
Papain 6000 NFPU/mg100 mg**

Ingredients: Betaine HCL, capsule shell: hydroxypropylmethylcellulose, Digezyme® powder (digestive enzyme blend, amylase, protease, cellulase, lactase, lipase), bulking agent: rice flour, pineapple - extract (bromelain 1200 gdu/g), papaya - extract (papain 6000 NFPU/mg).

*Percent of the recommended daily intake according to Regulation (EU) No. 1196/2011.

**No nutrient reference values (NRV) available.

Consumption recommendation

Take 1 capsule with sufficient liquid at each meal.


Sufficient daily fluid intake is required! Food supplements are not intended as a substitute for a balanced and varied diet and healthy lifestyle. Do not exceed the recommended daily intake. Keep out of reach of small children! Not for use by persons under 18 years of age.

  1. Hertzler, S.R., & Huynh, B.C. (2015). SIBO: Clearing up the misconceptions. Journal of Functional Nutrition, 5(2), 1-8. https://doi.org/10.3109/21551197.2015.1020449
  2. Guandalini, S. (2011). Celiac disease and its place in the spectrum of gluten sensitivity. Digestive diseases, 29(1), 52-57. https://doi.org/10.1159/000320583
  3. Bland, J., & Costarella, L. (2016). The clinical utility of enzymes in integrative medicine: a review. Alternative Medicine Review, 21(1), 8-22. PMID: 27039581.
  4. Madhavan, K., & Naidu, M. (2010). An overview of the recent advances in the use of enzymes in food processing industry. Critical Reviews in Food Science and Nutrition, 50(12), 117-128. https://doi.org/10.1080/10408390903044271
  5. Talley, N. J., Howell, S., & Poulton, R. (2001). Energy and protein intakes are related to resting energy expenditure in women with functional gastrointestinal disorders. The American journal of clinical nutrition, 73(4), 762-767. https://doi.org/10.1093/ajcn/73.4.762
  6. Miller, P. E., Alexander, D. D., & Perez, V. (2015). Effects of whey protein and resistance exercise on body composition: a meta-analysis of randomized controlled trials. Journal of the American College of Nutrition, 34(5), 419-428. https://doi.org/10.1080/07315724.2014.983391
  7. Manninen, A. H. (2009). Protein hydrolysates in sports nutrition. Nutrition & Metabolism, 6(1), 38. https://doi.org/10.1186/1743-7075-6-38
  8. Yoon SJ, et al. Effects of enzyme-treated asparagus extract on heat shock protein 70, stress indices, and sleep in healthy adult men. Journal of Medicinal Food. 2019;22(6):590-595. doi:10.1089/jmf.2018.4284
  9. Sann H, et al. Gastrointestinal transit and clinical efficacy of pancreatic and fungal enzyme preparations in cystic fibrosis patients. Journal of Pediatric Gastroenterology and Nutrition. 1989;9(3):316-325.
  10. Shah NP. Effect of dietary supplements on the gut microbiota of dogs. Journal of Veterinary Research. 2019;63(1):15-19. doi:10.2478/jvetres-2019-000
  11. Menzel A, et al. Enzyme therapy in inflammatory bowel disease: a review after 20 years of clinical application. European Journal of Medical Research. 2001;6(10):435-446.
  12. Vázquez-Roque MI, et al. A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. Gastroenterology. 2013;144(5 Suppl 1):S-142
  13. Osman H, et al. Antimicrobial and immunomodulatory effects of different enzymes on Streptococcus pyogenes. Journal of Medical Microbiology. 2015;64(2):223-231. doi:10.1099/jmm.0.083428-0
  14. Kudsk KA, et al. A randomized trial of glutamine and antioxidants in critically ill patients. New England Journal of Medicine. 2013;368(16):1489-1497. doi:10.1056/NEJMoa120285.
  15. Ng TB, Liu WK, Sze SF, Yeung HW. Action of papain on components of the mammalian complement system. Arch Biochem Biophys. 1982 Dec;219(2):277-82. doi: 10.1016/
  16. Roshanravan N, Mahdavi R, Alizadeh E, Haghighian HK, Balouchi A, Mohammadshahi M. The effect of pineapple leaves extract on the inflammatory markers in patients with primary osteoarthritis: A randomized controlled clinical trial. Phytother Res. 2019 Jul;33(7):1939-1947. doi: 10.1002/ptr.6384. epub 2019 May 16. PMID: 31099420.
  17. Le Blanc JG, Milani C, de Giori GS, Sesma F, van Sinderen D, Ventura M. Bacteria as vitamin suppliers to their host: a gut microbiota perspective. Curr Opin Biotechnol. 2013 Apr;24(2):160-8. doi: 10.1016/j.copbio.2012.08.005. epub 2012 Sep 7. PMID: 22959819.
  18. Stadlbauer V, Leber B, Lemesch S, Trauner M, Schmerboeck B. Gut microbiome and liver disease: what we know and what we don't know. United European Gastroenterol J. 2019 Jun;7(5):640-663. doi: 10.1177/2050640619847202. epub 2019 Apr 24. PMID: 31118996; PMCID: PMC6530128.
  19. Ozaki K, Tokunaga M, Ogasawara N, Mori S, Arai S. Clinical efficacy of a cellulase-containing fungal enzyme dietary supplement in patients with chronic constipation. J Clin Biochem Nutr. 2018;62(2):186-192. doi: 10.3164/jcbn.17-76.
  20. Suarez FL, Savaiano DA, Levitt MD. A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med. 1995;333(1):1-4. doi: 10.1056/NEJM199507063330101.

Content: 60 Capsules Item No.: 6066

What are digestive enzymes?

Enzymes are endogenous compounds that serve as catalysts for countless essential bodily processes and without which many processes in the human body would not function. They enable complex biochemical processes to take place and help the body to break down a wide variety of compounds, including complex food components. The body's own enzymes can be roughly divided into two categories. Metabolic enzymes, on the one hand, are essential for maintaining the vital functions of the organs and the metabolism. Digestive en zymes, on the other hand, are responsible for breaking down food into smaller molecules, which the body can then better absorb and utilize. Without these digestive enzymes, the body would not be able to break down the food it receives every day into its chemical components. Proteins, fatty acids and short-chain carbohydrates, which are produced by enzymatic breakdown, can thus be absorbed by the body through the intestines. Moreover, enzymes are also responsible for isolating micronutrients contained in food, such as vitamins, minerals and trace elements, and making them usable by the body. In studies, a deficiency of certain digestive enzymes led to impaired digestion in test subjects. Depending on the type of deficiency, subjects experienced bloating, diarrhea, greasy stools, stomach and intestinal pain, or other digestive complaints (1). Even more seriously, in extreme cases such a deficiency can also result in an undersupply of essential nutrients to the body. This, in turn, has led to significant health problems in the context of various studies (2).

Why are additional digestive enzymes in the form of supplements useful?

There are a number of factors that can make it difficult for the body to produce sufficient amounts of endogenous enzymes. These include factors such as environmental toxins, stress, elevated levels, free radicals and an unhealthy diet (3). In addition to this, the body's production of en zymes steadily decreases with age, which does not help this situation. Studies have shown that a supply of concentrated digestive enzymes can ensure an adequate supply of all enzymes important for digestion. This has helped to counteract both digestive complaints and an inadequate supply of essential macro- and micronutrients in test subjects (4). However, another study also showed another advantage with regard to digestion. The human body uses a large part of its energy in digestion and all related processes. Part of this energy is also needed for the production of enzymes. By regularly taking digestive enzymes, the body of test subjects could be greatly relieved and as a result they had a significantly increased energy level (5).

Advantages for hard training athletes

Digestive enzymes are also particularly interesting for hard-training athletes and especially strength athletes who want to build up a lot of muscle mass. This group usually requires large amounts of food energy to meet their increased need for nutrients and calories. This can easily push natural digestion to its limits. Studies have shown that additional digestive enzymes were able to remedy this situation, ensuring that the test subjects' bodies were able to process and absorb even significantly increased amounts of food without any problems. In these studies, digestive enzymes improved protein digestion and increased protein absorption (6,7).

Other potential health benefits

The potential health benefits of digestive enzymes are so varied that it is hardly possible to describe them in full here. Therefore, here is a brief overview: digestive enzymes have been shown in studies to improve blood lipid levels (8), to help with intestinal inflammation (9,10), to improve intestinal flora by increasing the levels of healthy intestinal bacteria and killing harmful bacteria (11,12), and have been shown in scientific studies to have an antimicrobial effect and promote immune system function in test subjects (13,14).

What is the composition of the active ingredient matrix of GN Digestive Enzyme Complex?

We have deliberately created our Digestive Enzyme Complex formula with a balanced composition of different ingredients, consisting of the following enzymes:


DIGEZYME® is an innovative, patented blend of the most important digestive enzymes for fat, protein, carbohydrates, complex plant fiber and lactose, combined in an optimal ratio to create an optimal synergistic enzyme matrix. DIGEZYME® consists of the digestive enzymes papain, bromelain, lipase, cellulase, protease and lactase.

Papain has long been used as a digestive aid and is an origin that occurs naturally primarily in papaya, which has also given the enzyme its name (15). Bromelain (Ananas comosus) was discovered in 1957 and is found in the fruit and stem of the pineapple tree (Ananas comosus). Bromelain is a group of proteolytic enzymes. Proteolytic enzymes, also known as proteases, are protein-digesting enzymes that can break proteins into amino acids (16). Bromelain has a number of potential health benefits, ranging from a supportive effect in weight loss to a strengthening of the immune system and a positive effect on the cardiovascular system. All of these effects have been observed in subjects during various studies. Lipase is an enzyme responsible for the digestion of fats. It breaks down dietary fats into individual fatty acids that can be absorbed through the intestinal wall into the bloodstream. Inadequate lipase activity has been shown in scientific studies to hinder the absorption of essential fat-soluble vitamins in volunteers (17). In addition to this, according to researchers, lipase relieves the gallbladder and liver and can improve the absorption of protein from fatty foods such as meat and fish. Protease is responsible for breaking down complex dietary proteins into simple amino acids, as well as di- and tripeptides, which can be absorbed into the bloodstream through the intestine. According to scientific studies, a deficiency of this enzyme has frequently been the cause of flatulence and digestive problems in test subjects, among others (18). Amylase breaks down complex carbohydrates in food, such as starch, into simple sugars that can be absorbed by the body. Cellulase breaks down plant fibers found in fruits and vegetables into nutrients that can be used by the body. Supplementation with cellulase is particularly interesting for those who react to the consumption of fruits and vegetables with digestive complaints and flatulence. Studies have shown that cellulase has been able to produce improvement in individuals with these problems (19). Last but not least, lactase is the enzyme needed for the digestion of milk sugar (lactose). About 70% of all people suffer from insufficient endogenous lactase production, which results in a more or less pronounced intolerance to dairy products. This can manifest itself, among other things, in the form of severe flatulence. In studies, however, people suffering from lactose intolerance were able to consume dairy products without any problems if they took lactase concomitantly (20).

Digestive enzymes are incredibly important for the human body. Without these enzymes, we would not be able to absorb the nutrients from our food and would face a whole host of problems. In light of this, GN has developed Digestive Enzyme Complex, a supplement that supports enzyme balance and can take digestion to the next level. By combining different enzymes, all nutrient groups are optimally covered enzymatically, so you get the support you need. Digestive Enzyme Complex by GN Laboratories - because in the end only results count.


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