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Nano Pure Citrulline Malate - 500g

Original price €26,90 - Original price €26,90
Original price €26,90
€26,90 - €26,90
Current price €26,90
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Citrulline is one of the three amino acids of the urea cycle. The intake of citrulline increases the plasma level of arginine in the blood and thus promotes nitric oxide metabolism. This allows the blood flow to increase significantly, resulting primarily in an incredible pump during training, improved regeneration and a better supply of nutrients to the muscles. Citrulline Malate from GN Laboratories brings you all the benefits of the amino acid - because in the end only results count

Product Highlights:

  • Incredible pump
  • Improved blood circulation
  • Pure L-Citrulline DL Malate 2:1
  • NanoPure® for pure purity
  • Easy to dose powder
  • Also available in capsule form
  • Proven quality - Made in Germany
Nutritional values and ingredients

Average nutritional values
per 100 gper 5 g% (NRV*)
L-Citrulline DL Malate 2:1100 g5 g**

Ingredients: L-Citrulline DL Malate 2:1 (vegan) NanoPure®.

*Percent of the recommended daily intake according to Regulation (EU) No. 1196/2011.

**No nutrient reference values (NRV) available.

Consumption recommendation

Take 5g of powder with plenty of liquid.


Not recommended for use by persons under 18 years of age. Do not exceed the specified recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of children.

  1. Pérez-Guisado, J., & Jakeman, P. M. (2010). Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. Journal of strength and conditioning research, 24(5), 1215-1222.
  2. Sureda, A., Córdova, A., Ferrer, M. D., Pérez, G., Tur, J. A., & Pons, A. (2010). L-citrulline-malate influence over branched chain amino acid utilization during exercise. European journal of applied physiology, 110(2), 341-351.
  3. Romero, M. J., Platt, D. H., Tawfik, H. E., Labazi, M., El-Remessy, A. B., Bartoli, M., ... & Caldwell, R. B. (2006). Diabetes-induced coronary vascular dysfunction involves increased arginase activity. Circulation research, 102(1), 95-102.
  4. Bailey, S. J., Blackwell, J. R., Lord, T., Vanhatalo, A., Winyard, P. G., & Jones, A. M. (2015). l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans. Journal of applied physiology, 119(4), 385-395.
  5. Suzuki, T., Morita, M., Kobayashi, Y., & Kamimura, A. (2016). Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: double-blind randomized placebo-controlled 2-way crossover study. Journal of the International Society of Sports Nutrition, 13(1), 6.
  6. Wanner, S. P., Gailly, P., & Brueggemann, G. P. (2002). Increased Ca2+ influx through L-type Ca2+ channels in dystrophic mdx mouse muscle? A critical reappraisal. American Journal of Physiology-Cell Physiology, 283(5), C1581-C1593.
  7. Rafikova, O., Meadows, M. L., Kinchen, J. M., Mohney, R. P., Maltepe, E., Desai, A. A., ... & Fineman, J. R. (2011). Metabolic changes precede the development of pulmonary hypertension in the chronically hypoxic newborn rat. American Journal of Physiology-Lung Cellular and Molecular Physiology, 300(5), L856-L865.
  8. Bendahan, D., Mattei, J. P., Ghattas, B., Confort-Gouny, S., Le Guern, M. E., & Cozzone, P. J. (2002). Citrulline/malate promotes aerobic energy production in human exercising muscle. British journal of sports medicine, 36(4), 282-289.
  9. Osowska, S., Duchemann, T., Walrand, S., Paillard, A., Boirie, Y., & Cynober, L. (2004). Citrulline modulates muscle protein metabolism in old malnourished rats. American Journal of Physiology-Endocrinology and Metabolism, 287(3), E529-E535.
  10. Glenn JM, Gray M, Wethington LN, Stone MS, Stewart RW Jr, Moyen NE. Acute citrulline-malate supplementation improves maximal strength and anaerobic power in female, masters athletes tennis players. Eur J Sport Sci. 2016;16(8):1095-103. doi: 10.1080/17461391.2016.1181198. epub 2016 Apr 26. PMID: 27109224.

Content: 500g Item No.: 8071

What is Citrulline Malate and how can Citrulline Malate maximize the pump?

Citrulline Malate is one of the three amino acids of the urea cycle that occurs naturally in the human body. In weight training and bodybuilding, citrulline is best known for its blood flow-enhancing properties, which can dramatically increase the pump effect during exercise (1). However, citrulline also has a variety of other benefits that can potentially benefit any athlete to improve recovery and performance (2). Citrulline acts by acting as a substrate for the arginine-nitric oxide synthase-nitric oxide pathway while stimulating the production of the enzyme nitric oxide synthase (3). Nitric oxide, as a messenger, elicits relaxation of vascular smooth muscle tissue. This, in turn, resulted in dilatation of the veins and thus potentially maximized blood flow in one study (4). According to scientific studies, a maximally increased blood supply to the muscles is synonymous with a maximum supply of oxygen. It also means a maximum supply of energy-providing nutrients and the body's own anabolic hormones. At the same time, the maximally increased blood flow also improves the removal of toxic metabolic products that are inevitably produced during intensive training sessions (5). This is important because as the amount of these toxic waste products increases, the contractility of the muscles continues to decrease (6). As an added bonus, nitric oxide improves muscle contractile function while increasing glucose uptake into the muscles (7). ATP production, and thus energy supply during exercise, is another factor that can benefit from citrulline ingestion (8). This effect is particularly important because citrulline also helps to reduce the toxic ammonia produced during exercise (9).

Studies have shown that all of these factors can lead to more repetitions per set or more training sets per session (1,4,5). As a result, citrulline supplementation was shown in one study to lead to improved growth stimulus during training (2,4).

How can citrulline malate accelerate recovery and maximize muscle growth?

After training, improved blood circulation inevitably results in a better supply of the muscles. Oxygen, nutrients and the body's own anabolic hormones reach the muscle cells more quickly due to an increased blood supply. This in turn results in faster and better regeneration (1). In addition, citrulline can reduce the occurrence of muscle soreness after training (10) , which allows a new growth stimulus to be set more quickly. Citrulline can also potentially support muscle growth via several independent effects. It increases muscle protein synthesis rates, allowing more muscle protein and therefore more muscle mass to be built in subjects of various studies (2,4). Also, the increase in muscle volume due to improved blood flow, possessed direct muscle building increasing effects in test subjects (8). Last but not least, the significantly stimulated blood flow through citrulline results in a stretching of the fascia. Scientific studies have shown that such repeated stretching of the fascia has direct anabolic, muscle-building effects (8).

Advantages of NanoPure® raw materials

NanoPure® is not just a manufacturer of various dietary supplements or ingredients, NanoPure® stands for the highest quality and maximum purity. All products, with the NanoPure® seal of approval, undergo the most stringent testing procedures before being released for sale. Independent laboratories test each batch to the highest scientific standards to ensure that no impurities can affect the quality of the products. Anyone who reads NanoPure® on a product can be sure that there are no heavy metals, no extenders and no contaminants in their product. NanoPure® stands for pure quality.

In conclusion, it can be said that citrulline shines through a whole range of benefits that can bring an intake with it. The positive effects clearly speak for themselves, which is why the question should not be why citrulline should be supplemented, but rather why someone should not do it? We can think of neither studies nor meaningful reasons for this. Citrulline Malate from GN Laboratories - because in the end only results count.

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