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Melatonin - 90 capsules

Melatonin - 90 capsules

from GN Laboratories
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€19,90
€19,90 - €19,90
€19,90
€14,90
€14,90 - €14,90
€14,90
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Melatonin is a neurohormonereleased in the brain to regulate sleep. regulate sleep. Sleep is an essential component of optimal regeneration and an incredibly important factor for the general health. Melatonin can help to fall asleep better at night and to get up with more energy in the morning. Melatonin from GN Laboratories - because in the end only results count.

  • Contributes to the normalization of the sleep rhythm
  • May facilitate falling asleep
  • Scientifically proven effect
  • Antioxidant properties
  • Easy to dose capsule form
  • Proven quality - made in Germany
Nutritional values and ingredients
Composition Per capsule % (NRV)
Melatonin 0,5 mg **


Ingredients: Releasing agent/filler: microcrystalline cellulose; melatonin.

*Percent of the recommended daily intake according to Regulation (EU) No. 1196/2011.

**No nutrient reference values (NRV) available.

Consumption recommendation

Consumption recommendation for GN Melatonin

Take 1 capsule 30-60 minutes before bedtime. Do not take another capsule in a 24 hour period.

Notes

Do not exceed the recommended daily intake stated. Food supplements are not a substitute for a balanced and varied diet. Food supplements should be kept out of the reach of children.

Sources
  1. Lemoine, P., Nir, T., Laudon, M., & Zisapel, N. (2007). Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. Journal of sleep research, 16(4), 372-380.
  2. Cajochen, C., Krauchi, K., & Wirz-Justice, A. (2003). Role of melatonin in the regulation of human circadian rhythms and sleep. Journal of neuroendocrinology, 15(4), 432-437.
  3. Garfinkel, D., Laudon, M., Nof, D., & Zisapel, N. (1995). Improvement of sleep quality in elderly people by controlled-release melatonin. The Lancet, 346(8974), 541-544.
  4. Fonken, L. K., & Nelson, R. J. (2014). The effects of light at night on circadian clocks and metabolism. Endocrine reviews, 35(4), 648-670. doi: 10.1210/er.2013-1051
  5. Maestroni, G. J. (1993). The immunoneuroendocrine role of melatonin. Journal of pineal research, 14(1), 1-10. doi: 10.1111/j.1600-079X.1993.tb00478.x
  6. Garfinkel, D., Laudon, M., Nof, D., & Zisapel, N. (1995). Improvement of sleep quality in elderly people by controlled-release melatonin. The Lancet, 346(8974), 541-544.
  7. National Sleep Foundation. (n.d.). Irregular sleep schedules: how they affect your sleep. Sleep Foundation. https://www.sleepfoundation.org/articles/irregular-sleep-schedules-how-they-affect-your-sleep.
  8. Skene, D. J., Arendt, J., & Cade, J. E. (2005). Use of melatonin in the treatment of phase shift and sleep disorders. Advances in therapy, 22(4), 337-351.
  9. Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database of Systematic Reviews. 2002;(2):CD001520. doi: 10.1002/14651858.CD001520
  10. Ferracioli-Oda, E., Qawasmi, A., & Bloch, M. H. (2013). Meta-analysis: melatonin for the treatment of primary sleep disorders. PloS One, 8(5), e63773. https://doi.org/10.1371/journal.pone.0063773.
  11. Dollins, A. B., Zhdanova, I. V., Wurtman, R. J., Lynch, H. J., & Deng, M. H. (1994). Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proceedings of the National Academy of Sciences, 91(5), 1824-1828.
  12. Reiter, R. J., Tan, D. X., Manchester, L. C., Qi, W., & Garcia, J. J. (2001). Melatonin reduces oxidant damage and promotes mitochondrial respiration: implications for aging. Annals of the New York Academy of Sciences, 939(1), 158-167.
  13. Amstrup, A. K., Sikjaer, T., Pedersen, S. B., Heickendorff, L., & Mosekilde, L. (2015). The effect of melatonin on the metabolic response to nocturnal life in type 2 diabetes. American Journal of Physiology-Endocrinology and Metabolism, 308(4), E343-E353.
  14. Gao, Y., Xu, Y., & Guo, Y. (2019). Melatonin supplementation and gastrointestinal tract: impact and possible effects. World Journal of Gastroenterology, 25(32), 4850-4861. https://doi.org/10.3748/wjg.v25.i32.4850.
  15. Ohayon MM. "Epidemiology of insomnia: what we know and what we still need to learn." Sleep Med Rev. 2002 Apr;6(2):97-111. doi: 10.1053/smrv.2001.0186. PMID: 12531146.

Content: 90 capsules Item No.: 8006

Melatonin is secreted in the human brain in the pineal gland and is responsible for regulation of the body's biological of the body (1). The melatonin production in our body is strongly dependent on our living conditions and is mainly influenced above all by light. In daylight, the pineal gland produces the neurotransmitter serotonin. At night, however, the production of serotonin is stopped and melatonin is produced instead (2). The production of melatonin varies depending on the amount of light to which we areto which one is exposed. More melatonin is produced at night than during the day, and the body produces more melatonin in a completely darkened room than in a semi-dark room (3). Especially in big cities, brightness and the light pollution that comes with it is a steadily growing problem.. This can sometimes lead to the fact that melatonin production in the brain cannot take place without restrictions (4). Stress, disease, and aging are also factors that can affect melatonin levels (1,5). A deficiency of the hormone has been shown in studies to lead to insomnia (6). (6). Insomnia and irregular sleep habits are associated with a a variety of health problems and premature aging (1,7). There are populations that are often prone to impaired production of melatonin. Studies have shown that especially older people produce less melatonin on average (8). (8). The same is true for people who work shift work work or who regularly have to deal with jet have to fight. Here, too, a study showed that the regular intake of melatonin helped the subjects (9). Since melatonin can be supplied externally, it is finding increasing increasingly popular in the form of dietary supplements.. The intake of melatonin is considered to be an effective way to improve overall sleep quality and to maintain maintain a regular sleep schedule (10). (10). Subjects in one study reported a calmer and deeper sleep (11).

In addition to the regulating effect on sleep, melatonin also has numerous other numerous other positive effects. The hormone has a strong antioxidant effect (8,12). Antioxidants such as melatonin work by counteracting oxidative stress in the body. Oxidative stress is a result of the production of so-called free radicals. These are produced during normal metabolic processes, as well as by various environmental factors. Metabolism also appears to be affected by melatonin. While studies have not shown a correlation between the hormone and lean body mass. However, melatonin did help in one study, prevent the body from putting on extra fat (13). (13). Regular intake of the vitamin has also been shown to have a positive effect on stomach health in scientific studies. positively on the stomach health (14).

In summary, melatonin is a really important hormone in the human body whose importance is directly related to sleep. Without a normal night sleep, many functions of the human body can not run optimally (15). Melatonin from GN Laboratories - Health Line can help to ensure that the Melatonin levels reach an optimal level.. So nothing stands in the way of sleep and regeneration. Melatonin from GN Laboratories - Health Line Because in the end only results count.

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