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Curcumin Plus - 60 capsules

Curcumin Plus - 60 capsules

from GN Laboratories
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€19,90 - €19,90
€19,90
€19,90
€19,90 - €19,90
€19,90
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Curcumin offers numerous positive effects for the human organism. More and more people benefit from curcumin when it comes to their digestion, inflammations or the regeneration after a hard workout. Curcumin Plus from GN delivers the potent active ingredient in optimally absorbable form, easy to dose and in the usual top quality.

  • Highly concentrated, with 95% curcuminoids guaranteed.
  • 500 mg curcumin extract 50:1
  • Optimal absorption due to the addition of piperine
  • High bioavailability
  • Easy to dose capsule form
  • Highest quality - Made in Germany
Nutritional values and ingredients
CompositionPer capsule% (NRV*)
Kurckma extract250 mg**
thereof curcuminoids237.5 mg**
MKT5 mg**
black pepper extract 3 mg**
thereof piperine2.85 mg**


Ingredients: Curcuma longa L. Curcumin 95% (Curcumin Granular) HLPC, bulking agent: microcrystalline cellulose, capsule shell: hydroxypropyl methylcellulose, vegetable fat powder (from canola, contains medium chain triglycerides (MKT)), black pepper extract (contains 95% piperine).

*Percent of the recommended daily intake according to Regulation (EU) No. 1196/2011.

**No nutrient reference values (NRV) available.

Consumption recommendation

Take 1-2 capsule a day with plenty of liquid.

Notes

Food supplements are not intended as a substitute for a balanced and varied diet and healthy lifestyle. Do not exceed the recommended daily intake. Keep out of reach of small children!

Sources
  1. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 May;64(4):353-6. doi: 10.1055/s-2006-957450. PMID: 9619120.
  2. Panahi Y., Hosseini M.S., Khalili N., Naimi E., Simental-Mendia L.E., Majeed M., Sahebkar A. Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial. Biomed. Pharmacother. 2016;82:578-582. doi: 10.1016/j.biopha.2016.05.037.
  3. Aggarwal B.B., Harikumar K.B. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int. J. Biochem. Cell Biol. 2009;41:40-59. doi: 10.1016/j.biocel.2008.06.010.
  4. Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007;595:105-25. doi: 10.1007/978-0-387-46401-5_3. PMID: 17569207
  5. Suhett LG, de Miranda Monteiro Santos R, Silveira BKS, Leal ACG, de Brito ADM, de Novaes JF, Lucia CMD. Effects of curcumin supplementation on sport and physical exercise: a systematic review. Crit Rev Food Sci Nutr. 2021;61(6):946-958. doi: 10.1080/10408398.2020.1749025. epub 2020 Apr 13. PMID: 32282223.
  6. Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2889-2895. doi: 10.1080/10408398.2015.1077195. PMID: 26528921.
  7. Alkadi H. A Review on Free Radicals and Antioxidants. Infect Disord Drug Targets. 2020;20(1):16-26. doi: 10.2174/1871526518666180628124323. PMID: 29952268.
  8. Sharma GN, Gupta G, Sharma P. A Comprehensive Review of Free Radicals, Antioxidants, and Their Relationship with Human Ailments. Crit Rev Eukaryot Gene Expr. 2018;28(2):139-154. doi: 10.1615/CritRevEukaryotGeneExpr.2018022258. PMID: 30055541.
  9. Kwiecien S, Magierowski M, Majka J, Ptak-Belowska A, Wojcik D, Sliwowski Z, Magierowska K, Brzozowski T. Curcumin: A Potent Protectant against Esophageal and Gastric Disorders. Int J Mol Sci. 2019 Mar 24;20(6):1477. doi: 10.3390/ijms20061477. PMID: 30909623; PMCID: PMC6471759.
  10. Lopresti AL, Smith SJ, Rea A, Michel S. Efficacy of a curcumin extract (Curcugen™) on gastrointestinal symptoms and intestinal microbiota in adults with self-reported digestive complaints: a randomised, double-blind, placebo-controlled study. BMC Complement Med Ther. 2021 Jan 21;21(1):40. doi: 10.1186/s12906-021-03220-6. PMID: 33478482; PMCID: PMC7818735.
  11. Goodman BE. Insights into digestion and absorption of major nutrients in humans. Adv Physiol Educ. 2010 Jun;34(2):44-53. doi: 10.1152/advan.00094.2009. PMID: 20522896.
  12. Gorissen SH, Rémond D, van Loon LJ. The muscle protein synthetic response to food ingestion. Meat Sci. 2015 Nov;109:96-100. doi: 10.1016/j.meatsci.2015.05.009. epub 2015 May 20. PMID: 26021783.
  13. Gwin JA, Church DD, Wolfe RR, Ferrando AA, Pasiakos SM. Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit. Nutrients. 2020 Aug 15;12(8):2457. doi: 10.3390/nu12082457. PMID: 32824200; PMCID: PMC7469068.
  14. Liang Z, Xue Y, Wang T, Xie Q, Lin J, Wang Y. Curcumin inhibits the migration of osteoclast precursors and osteoclastogenesis by repressing CCL3 production. BMC Complement Med Ther. 2020 Jul 23;20(1):234. doi: 10.1186/s12906-020-03014-2. PMID: 32703287; PMCID: PMC7379354.
  15. Heshmati J, Moini A, Sepidarkish M, Morvaridzadeh M, Salehi M, Palmowski A, Mojtahedi MF, Shidfar F. Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trial. Phytomedicine. 2021 Jan;80:153395. doi: 10.1016/j.phymed.2020.153395. epub 2020 Oct 22. PMID: 33137599.
  16. Qin S, Huang L, Gong J, Shen S, Huang J, Ren H, Hu H. Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials. Nutr J. 2017 Oct 11;16(1):68. doi: 10.1186/s12937-017-0293-y. PMID: 29020971; PMCID: PMC5637251.
  17. Marton LT, Pescinini-E-Salzedas LM, Camargo MEC, Barbalho SM, Haber JFDS, Sinatora RV, Detregiachi CRP, Girio RJS, Buchaim DV, Cincotto Dos Santos Bueno P. The Effects of Curcumin on Diabetes Mellitus: A Systematic Review. Front Endocrinol (Lausanne). 2021 May 3;12:669448. doi: 10.3389/fendo.2021.669448. PMID: 34012421; PMCID: PMC8126655.
  18. Saadati S, Sadeghi A, Mansour A, Yari Z, Poustchi H, Hedayati M, Hatami B, Hekmatdoost A. Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial. BMC Gastroenterol. 2019 Jul 25;19(1):133. doi: 10.1186/s12876-019-1055-4. PMID: 31345163; PMCID: PMC6659284.

Content: 60 capsules Item No.: 5285

Curcumin is, as the name suggests, derived from the turmeric plant plant and is a naturally occurring Curcuminoid. In several studies, the active ingredient has been a whole range of positive effects on health have been attributed to the active ingredient. It is little wonder that the turmeric plant has been used for for thousands of years in the context of traditional Chinese medicine, as well as in the Indian area application finds. Also here with us curcumin is gaining as a dietary supplement more and more popular. However, there are a few things to keep in mind when supplementing with curcumin. When taken orally, the active ingredient is largely destroyed by the liver during the so-called "first pass". As a result, only a fraction of curcumin can be absorbed by the body, which would ultimately have little benefit to our organism. Curcumin Plus from GN Laboratoriescircumvents these hurdles through the addition of piperine. Scientific studies have shown that Piperineextracted from black pepper, is capable of effectively inhibiting the effectively inhibit the degradation process of curcumin in the human liver.. Thereby increases piperine increases the bioavailability of curcumin by up to no less than 2000 % (1). Curcumin Plus from GN Laboratories can therefore be optimally optimally absorbed absorbed by the body, which positive properties on the health can unfold to the fullest extent.

The anti-inflammatory properties are probably the most frequently demonstrated effect of curcumin in studies. With regard to this property, numerous studies have concluded that the ingestion of curcumin sets in motion various mechanisms that have been shown in the subjects to demonstrably have been shown to reduce reduce inflammation (2,3,4). Sometimes these anti-inflammatory properties led to in the context of further studies, Effectively promote regeneration processes. Due to this effect, the intake of curcumin in the participants of one study contributed to improve performance in sports (5). In addition to these effects, curcumin also exhibits a strong antioxidant effect . These, as well as the anti-inflammatory properties, have been been proven by numerous studies. In the test groups of various studies, curcumin was thus able to contribute to the the optimal function of the body's cells (4,6). (4,6). Antioxidants protect the human organism from oxidative stress. Oxidative stress leads to the formation of free radicals and can thus damage the body's cells in various ways. Free radicals restrict the synthesis of various proteins, and these restricted endogenous proteins include muscle cells. Thus, restricted protein biosynthesis leads to reduced muscle growth. In addition, free radicals deactivate important enzymes in our body and can damage cell membranes (7,8). However, the benefits of curcumin do not stop with the antioxidant effect. Through various studies, the intake of curcumin has been shown to have a regulating effect on digestion has been proven. The compound has been shown to be potentially supportive in a variety of digestive problems among subjects in several research studies (9,10). The intestines and digestion are crucial aspects of health in general. However, for athletes in particular, they are especially important from another perspective. Digestion is crucial to, how efficiently the human organism can absorb nutrients (11). This absorption of nutrients, in turn, is a factor for optimal muscle development (12,13). (12,13).

The various benefits that a regular intake of curcumin can bring go far beyond this brief list. In one study it showed an inhibitory effect on the development of osteoclasts (14). (14). Osteoclasts are responsible for the breakdown of bone substance and can significantly reduce bone density. Curcumin had a regulating effect on regulating the blood glucose level (15). This effect is based, among other things, on the fact that curcumin has the ability to stimulate the beta cells of the pancreas. These in turn are responsible for the production of insulin in our body. In addition lowered Curcumin reduced cholesterol and triglyceride levels (16,17) after only one week of intake in study participants and had a protective effect on the liver. protective effect on the liver (18).

Curcumin Plus by GN Laboratories delivers all the benefits of the extraordinary active ingredient in the top quality you have come to expect from GN. Take advantage of the positive effects of a plant that has been appreciated for thousands of years for its effects. Curcumin Plus, so that nothing stands in the way of your goals.

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